Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676294 | 0.82 | TDP1 (0.41) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL11508590 | 0.77 | TDP1 (0.38) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL6038534 | 0.73 | ERN1 (0.41) | ALDH1A1HPGDTDP1KDM4ECYP1A2 | |
| SCHEMBL3126914 | 0.72 | CYP3A4 (0.58) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL439080 | 0.68 | MAPT (0.40) | ALDH1A1HPGDTDP1KDM4EMAPT | |
| SCHEMBL28167698 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL27512917 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HPGDTDP1KDM4EL3MBTL1 | |
| SCHEMBL27189267 | 0.68 | CYP3A4 (0.53) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL30701949 | 0.67 | CA9 (0.50) | ALDH1A1HPGDTDP1CYP3A4KDM4E | |
| SCHEMBL3674074 | 0.67 | CA9 (0.50) | ALDH1A1HPGDTDP1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060210452-A1 | Very large scale immobilized polymer synthesis | AFFYMAX TECHNOLOGIES, N.V., A NETHERLANDS ANTILLES CORPORATION | 2006-09-21 | — | — | US | disclosed |
| US-20060194258-A1 | Polypeptide array synthesis | AFFYMETRIX, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| US-7087732-B2 | Nucleotides and analogs having photoremovable protecting groups | AFFYMETRIX, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919211-B1 | Polypeptide arrays | AFFYMETRIX, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050153362-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050153363-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050118706-A1 | Polymer arrays | AFFYMETRIX, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050095652-A1 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-05-05 | — | — | US | disclosed |
| US-6124102-A | EVALUATING THE BINDING OF COMPOUNDS TO BINDING PROTEINS; INCUBATION OF LABELLED BINDING PROTEIN TO SUBSTRATE, ANALYZE PIXEL INTENSITY AT KNOWN POSITIONS, USE COMPUTER TO ANALYZE RELATIVE BINDING OF COMPOUNDS TO BINDING PROTEIN | AFFYMETRIX, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5889165-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753788-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5744101-A | Photolabile nucleoside protecting groups | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-28 | — | — | US | disclosed |
| US-5744305-A | Arrays of materials attached to a substrate | AFFYMETRIX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5489678-A | 6-NITRO-1,3-BENZOXAZOL-5-YL ALKYLOXY PROTECTIVE GROUP ON THE 5' POSITION OF A DEOXYNUCLEOSIDE; COMPUTERIZED SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-02-06 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| EP-0562025-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0562025-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010092-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194258-A1 | Polypeptide array synthesis | MRPL21, NGLY1, PSAP | ALDH1A1 4233/4885HPGD 4108/4885TDP1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.