Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EDNRB | P24530 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038605 | 0.92 | KMT2A (0.54) | EDNRAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6039217 | 0.91 | MEN1 (0.51) | EDNRATDP1EDNRBMEN1KMT2A | |
| SCHEMBL6038942 | 0.87 | KMT2A (0.51) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL6038663 | 0.87 | LMNA (0.53) | ALDH1A1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL6038410 | 0.86 | KMT2A (0.53) | EDNRAALDH1A1HTTPOLBTDP1 | |
| SCHEMBL6039144 | 0.86 | AR (0.60) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL6038739 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HTTPOLBNPSR1KDM4E | |
| SCHEMBL6038795 | 0.84 | KMT2A (0.50) | ALDH1A1LMNAHTTSMN1; SMN2POLB | |
| SCHEMBL6038710 | 0.84 | AR (0.53) | EDNRAALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL6038781 | 0.84 | CCR4 (0.60) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1541563-A1 | CCR4 ANTAGONIST AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | CCR4, CCR1, CCR9 | EDNRA 512/4885ALDH1A1 2902/4885LMNA 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.