Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3999543 | 0.97 | ALDH1A1 (0.50) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL11284764 | 0.97 | ALDH1A1 (0.50) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL15192539 | 0.94 | — | — | |
| SCHEMBL3736701 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL8288869 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL19484952 | 0.80 | CYP1A2 (0.59) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL109476 | 0.78 | ALDH1A1 (0.42) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL10121133 | 0.78 | CYP1A2 (0.64) | HPGDKMT2ATDP1LMNAGAA | |
| SCHEMBL11889662 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL4840666 | 0.78 | ALDH1A1 (0.61) | ALDH1A1ATMHPGDMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101618462-B | Method for producing metal nanoparticles | DONGJIN SEMICHEM CO LTD | 2014-09-10 | — | — | CN | claimed |
| CN-101618462-A | Method for manufacturing metal nanometer particle | DONGJIN SEMICHEM CO LTD | 2010-01-06 | — | — | CN | claimed |
| US-20190092771-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2019-03-28 | — | — | US | disclosed |
| US-10174026-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |
| US-20180105521-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-04-19 | — | — | US | disclosed |
| US-9873697-B2 | Histone demethylase inhibitors | Celgene Quantical Research, Inc. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-11-02 | — | — | US | disclosed |
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9738637-B2 | Histone demethylase inhibitors | Celgene Quantical Research, Inc. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160199355-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MAYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | US | disclosed |
| CN-101618462-B | Method for producing metal nanoparticles | DONGJIN SEMICHEM CO LTD | 2014-09-10 | — | — | CN | disclosed |
| US-20130183269-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-18 | — | — | US | disclosed |
| CN-101618462-A | Method for manufacturing metal nanometer particle | DONGJIN SEMICHEM CO LTD | 2010-01-06 | — | — | CN | disclosed |
| CN-1929921-A | Use of a composition comprising metal complex compounds and polyphosphonates as catalysts for oxidations | CIBA SC HOLDING AG (CH) | 2007-03-14 | — | — | CN | disclosed |
| CN-1929920-A | Use of metal complex compounds comprising pyridine, pyrimidine or S-triazine derived ligands as catalysts for oxidations with organic peroxy acids and/or precursors of organic peroxy acids and H2O2 | CIBA SC HOLDING AG (CH) | 2007-03-14 | — | — | CN | disclosed |
| EP-1276491-B9 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | UNIV PENNSYLVANIA (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |
| CN-1252806-A | Dolastatin-15 derivatives having carbonyl and heterocyclic functional groups at the C-terminus | BASF AG (DE) | 2000-05-10 | — | — | CN | disclosed |
| CN-1252085-A | Fluorescent compositions and their use | CIBA SC HOLDING AG (CH) | 2000-05-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | ALDH1A1 437/4885ATM 2933/4885HPGD 355/4885 |
| US-20130183269-A1 | Hepatitis C Virus Inhibitors | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 3966/4885ATM 3039/4885HPGD 3868/4885 |
| US-20190092771-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | ALDH1A1 437/4885ATM 2933/4885HPGD 355/4885 |
| US-20160199355-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 3966/4885ATM 3039/4885HPGD 3868/4885 |
| US-20180105521-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | ALDH1A1 437/4885ATM 2933/4885HPGD 355/4885 |
| US-10174026-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, KDM5A | ALDH1A1 437/4885ATM 2933/4885HPGD 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.