Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417786 | 0.81 | ALDH1A1 (0.54) | EPHX2ALDH1A1NPC1RAB9ALMNA | |
| Trifluoroacetic Acid SCHEMBL6039700 | 0.80 | ALDH1A1 (0.47) | EPHX2ALDH1A1NPC1RAB9ALMNA | |
| Trifluoroacetic Acid SCHEMBL27829954 | 0.79 | BTK (0.49) | EPHX2KMT2AKCNA3CTSK | |
| Trifluoroacetic Acid SCHEMBL27848408 | 0.74 | BTK (0.51) | EPHX2KMT2AKCNA3CTSK | |
| SCHEMBL4637428 | 0.74 | TSHR (0.55) | EPHX2ALDH1A1KCNA3CTSKBRD4 | |
| Alcohol SCHEMBL28064671 | 0.71 | BTK (0.48) | EPHX2KMT2AKCNA3CTSK | |
| SCHEMBL56856 | 0.71 | EPHX1 (0.53) | EPHX2KMT2AKCNA3CTSK | |
| SCHEMBL19863558 | 0.71 | EPHX2 (0.52) | EPHX2KCNA3CTSKBRD4 | |
| Ammonia Solution, Strong SCHEMBL15021680 | 0.70 | EPHX1 (0.52) | EPHX2KMT2AKCNA3CTSK | |
| Hydrochloric Acid SCHEMBL4158527 | 0.70 | EPHX1 (0.52) | EPHX2KMT2AKCNA3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |