Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665848 | 0.81 | NPSR1 (0.35) | CYP4F2CYP4A11USP2 | |
| SCHEMBL1185969 | 0.77 | CTSK (0.31) | CTSK | |
| SCHEMBL3668825 | 0.75 | — | — | |
| SCHEMBL8887387 | 0.74 | CTSK (0.31) | CTSKCYP4F2CYP4A11 | |
| SCHEMBL27378855 | 0.67 | PPIA (0.38) | CTSKCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL4309286 | 0.67 | GRIN2B (0.40) | CTSKUSP2SMN1; SMN2 | |
| SCHEMBL4437296 | 0.67 | GRIN2B (0.40) | CTSKUSP2SMN1; SMN2 | |
| SCHEMBL692636 | 0.67 | GRIN2B (0.40) | CTSKUSP2SMN1; SMN2 | |
| SCHEMBL19281600 | 0.66 | CYP4F2 (0.35) | CTSKCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL1268184 | 0.66 | GRIN2B (0.41) | CTSKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |