Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 7/20 | 0.33 |
| ▸ | ADH1C | P00326 | 4/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954034 | 0.76 | ADH1A (0.36) | ADH1AADH1CFDPSALDH1A1ADH4 | |
| SCHEMBL7742694 | 0.73 | ADH1A (0.41) | ADH1AADH1CFDPSALDH1A1 | |
| SCHEMBL740408 | 0.73 | ADH1A (0.41) | ADH1AADH1CFDPSALDH1A1 | |
| SCHEMBL6039331 | 0.71 | CYP2D6 (0.31) | ADH1AADH1C | |
| SCHEMBL4520995 | 0.70 | HRH4 (0.38) | ADH1AADH1CALDH1A1ADH4 | |
| SCHEMBL6039748 | 0.70 | ADH1A (0.44) | ADH1AADH1CFDPSALOX5PHGDH | |
| SCHEMBL7748097 | 0.69 | DPP4 (0.36) | ALOX5ALDH1A1 | |
| SCHEMBL7747179 | 0.69 | DPP4 (0.36) | ALOX5ALDH1A1 | |
| SCHEMBL7742436 | 0.69 | DPP4 (0.36) | ALOX5ALDH1A1 | |
| SCHEMBL4242654 | 0.69 | ADH1A (0.46) | ADH1AADH1CPHGDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |