Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 11/20 | 0.44 |
| ▸ | ADH1C | P00326 | 8/20 | 0.43 |
| ▸ | ADH4 | P08319 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569527 | 0.79 | ALDH1A1 (0.43) | ADH1AADH1CADH4ALDH1A1PHGDH | |
| SCHEMBL18841480 | 0.75 | ADH1A (0.48) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL29957190 | 0.71 | ADH1A (0.54) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL3938593 | 0.71 | ADH1A (0.54) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL784985 | 0.71 | ADH1A (0.40) | ADH1AADH1CADH4 | |
| SCHEMBL4242654 | 0.70 | ADH1A (0.46) | ADH1AADH1CALDH1A1PHGDH | |
| SCHEMBL8905856 | 0.70 | ADH1A (0.54) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL6039335 | 0.70 | ADH1A (0.41) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL6039709 | 0.70 | ADH1A (0.33) | ADH1AADH1CADH4FDPSALOX5 | |
| SCHEMBL29957698 | 0.68 | ADH1A (0.50) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |