Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6039744

CCc1cc(C(C)(C)C)c([O-])c(C(C)(C)C)c1.[Cl-].[Zr+2]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.48
ALDH1A1 P00352 9/20 0.34
TSHR P16473 3/20 0.34
LMNA P02545 3/20 0.34
GAA P10253 1/20 0.34
CYP1A2 P05177 3/20 0.33
MAPK1 P28482 3/20 0.33
ALOX15 P16050 3/20 0.33
MEN1 O00255 2/20 0.33
CYP3A4 P08684 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 2/20 0.33
HIF1A Q16665 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CYP2C9 P11712 2/20 0.33
GMNN O75496 1/20 0.33
GABBR2 O75899 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6349436 0.91 HSPA5 (0.48) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL6356729 0.89 HSPA5 (0.47) HSPA5ALDH1A1TSHRLMNAGAA
Hydrochloric Acid SCHEMBL6039890 0.78 HSPA5 (0.41) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL25477939 0.75 HSPA5 (0.53) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL2177579 0.75 HSPA5 (0.53) HSPA5ALDH1A1TSHRLMNAGAA
Butylated Hydroxytoluene SCHEMBL6039994 0.75 ALDH1A1 (0.52) HSPA5ALDH1A1TSHRLMNACYP1A2
SCHEMBL11549682 0.74 ALDH1A1 (0.34) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL39434 0.73 HSPA5 (0.74) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL1930161 0.73 HSPA5 (0.52) HSPA5ALDH1A1TSHRLMNAGAA
SCHEMBL28409879 0.71 HSPA5 (0.50) HSPA5ALDH1A1TSHRLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7053160-B1 Metallocene monohalogenides BASELL POLYOLEFINE GMBH (DE) 2006-05-30 US claimed