Alanine

Alanine

SCHEMBL6040106

COC(=O)Cc1ccccc1.C[C@H](N)C(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.61
TSHR P16473 1/20 0.59
CYP4F2 P78329 1/20 0.54
CYP4A11 Q02928 1/20 0.54
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 2/20 0.51
LMNA P02545 1/20 0.51
HPGD P15428 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
MAPK1 P28482 1/20 0.49
PAM P19021 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
KLK7 P49862 1/20 0.45
LTA4H P09960 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL6040105 1.00 SLC7A5 (0.61) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Threonine SCHEMBL6040179 0.87 SLC7A5 (0.56) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Threonine SCHEMBL6040177 0.87 SLC7A5 (0.56) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL1870609 0.87 ALDH1A1 (0.62) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Benzene SCHEMBL28096336 0.87 ALDH1A1 (0.62) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL4675 0.87 ALDH1A1 (0.62) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Homoserine SCHEMBL6040192 0.86 SLC7A5 (0.62) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Homoserine SCHEMBL6040189 0.86 SLC7A5 (0.62) SLC7A5TSHRCYP4F2CYP4A11ALDH1A1
Dl-Phenylalanine SCHEMBL6040139 0.85 SLC7A5 (0.78) SLC7A5TSHRALDH1A1KDM4ELMNA
Phenylalanine SCHEMBL6040140 0.85 SLC7A5 (0.78) SLC7A5TSHRALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695088-A1 METHOD FOR ANALYSING METABOLITES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2006-08-30 EP disclosed
WO-2005059556-A1 METHOD FOR ANALYSING METABOLITES MAX PLANCK GESELLLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2005-06-30 WO disclosed