Threonine

Threonine

SCHEMBL6040177

CC(O)C(N)C(=O)O.COC(=O)Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
TSHR P16473 1/20 0.53
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.46
SLC1A3 P43003 4/20 0.45
SLC1A2 P43004 4/20 0.45
SLC1A1 P43005 4/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL6040179 1.00 SLC7A5 (0.56) SLC7A5TSHRALDH1A1KDM4ELMNA
Alanine SCHEMBL6040106 0.87 SLC7A5 (0.61) SLC7A5TSHRALDH1A1KDM4ELMNA
Alanine SCHEMBL6040105 0.87 SLC7A5 (0.61) SLC7A5TSHRALDH1A1KDM4ELMNA
Isoleucine SCHEMBL6040097 0.85 SLC7A5 (0.53) SLC7A5TSHRALDH1A1KDM4ELMNA
Isoleucine SCHEMBL6040098 0.85 SLC7A5 (0.53) SLC7A5TSHRALDH1A1KDM4ELMNA
Benzene SCHEMBL28096336 0.82 ALDH1A1 (0.62) SLC7A5TSHRALDH1A1KDM4ELMNA
SCHEMBL1870609 0.82 ALDH1A1 (0.62) SLC7A5TSHRALDH1A1KDM4ELMNA
SCHEMBL4675 0.82 ALDH1A1 (0.62) SLC7A5TSHRALDH1A1KDM4ELMNA
SCHEMBL8644205 0.80 TSHR (0.54) SLC7A5TSHRALDH1A1SLC1A3SLC1A2
Dl-Phenylalanine SCHEMBL6040139 0.80 SLC7A5 (0.78) SLC7A5TSHRALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695088-A1 METHOD FOR ANALYSING METABOLITES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2006-08-30 EP disclosed
WO-2005059556-A1 METHOD FOR ANALYSING METABOLITES MAX PLANCK GESELLLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2005-06-30 WO disclosed