⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469878 | 0.74 | — | — | |
| SCHEMBL6469566 | 0.70 | — | — | |
| SCHEMBL9860763 | 0.69 | — | — | |
| SCHEMBL27470402 | 0.63 | — | — | |
| Propylamine SCHEMBL29070629 | 0.61 | HSP90AA1 (0.33) | — | |
| SCHEMBL18160602 | 0.61 | — | — | |
| Monoethanolamine SCHEMBL28274591 | 0.61 | ALDH1A1 (0.33) | — | |
| SCHEMBL3152779 | 0.60 | — | — | |
| SCHEMBL24373234 | 0.59 | — | — | |
| SCHEMBL11153622 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049443-B2 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY (US) | 2006-05-23 | — | — | US | disclosed |
| US-6825225-B2 | useful against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci and streptococci, anaerobic organisms such as bacteroides and clostridia species, and acid-fast organisms | PHARMACIA & UPJOHN COMPANY | 2004-11-30 | — | — | US | disclosed |
| EP-1268475-B1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20040116413-A1 | Novel bicyclic isoxazolinones as antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2004-06-17 | — | — | US | disclosed |
| US-20040014967-A1 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY | 2004-01-22 | — | — | US | disclosed |
| EP-1334090-A1 | NOVEL BICYCLIC ISOXAZOLINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |
| EP-1268475-A1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002102785-A1 | NOVEL BICYCLIC ISOXAZOLINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |
| US-20020143009-A1 | Novel bicyclic oxazolidinones as antibacterial agents | PHARMACIA & UPJOHN | 2002-10-03 | — | — | US | disclosed |
| US-6387896-B1 | GRAMNEGATIVE, GRAMPOSITVE BACTERIA | PHARMACIA & UPJOHN CO. | 2002-05-14 | — | — | US | disclosed |
| US-6365612-B2 | Benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2002-04-02 | — | — | US | disclosed |
| EP-1181288-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| US-20010047018-A1 | Novel benzosultam oxazolidinone antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2001-11-29 | — | — | US | disclosed |
| WO-2001074812-A1 | NOVEL BENZOSULTAM OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-11 | — | — | WO | disclosed |
| WO-2000073301-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2000-12-07 | — | — | WO | disclosed |