Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.65 |
| ▸ | EGFR | P00533 | 6/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.62 |
| ▸ | VCP | P55072 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TLR4 | O00206 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525619 | 1.00 | FBP1 (0.65) | FBP1EGFRERBB2VCPLMNA | |
| SCHEMBL16267489 | 0.88 | EGFR (0.65) | FBP1EGFRERBB2VCPTLR4 | |
| SCHEMBL16267488 | 0.86 | FBP1 (0.64) | FBP1EGFRERBB2LMNAMAPT | |
| SCHEMBL16267490 | 0.86 | FBP1 (0.64) | FBP1EGFRERBB2LMNAMAPT | |
| SCHEMBL6041116 | 0.83 | EGFR (0.69) | FBP1EGFRERBB2VCPLMNA | |
| SCHEMBL2451780 | 0.82 | MAPT (0.81) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11354408 | 0.82 | MAPT (0.81) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10941162 | 0.82 | MAPT (0.81) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3235505 | 0.81 | FBP1 (0.68) | FBP1EGFRERBB2VCPTLR4 | |
| SCHEMBL3235501 | 0.81 | FBP1 (0.68) | FBP1EGFRERBB2VCPTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199255-A1 | Reagents for improved cell-based assays | BECKMAN COULTER INC. (US) | 2006-09-07 | — | — | US | disclosed |
| US-4148795-A | Dithiocarbamate ester bactericides and fungicides | AMERICAN CYANAMID COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4038288-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4011230-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-03-08 | — | — | US | disclosed |