Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.69 |
| ▸ | VCP | P55072 | 1/20 | 0.64 |
| ▸ | FBP1 | P09467 | 7/20 | 0.59 |
| ▸ | TLR4 | O00206 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929272 | 0.85 | EGFR (0.70) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL11236291 | 0.84 | EGFR (0.75) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL11236295 | 0.84 | EGFR (0.75) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL5070896 | 0.84 | KMT2A (0.61) | EGFRERBB2KMT2AALDH1A1LMNA | |
| SCHEMBL6584626 | 0.83 | TLR4 (0.64) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL5929443 | 0.83 | EGFR (0.74) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL6041047 | 0.83 | FBP1 (0.65) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL11525619 | 0.83 | FBP1 (0.65) | EGFRERBB2VCPFBP1TLR4 | |
| SCHEMBL16267488 | 0.82 | FBP1 (0.64) | EGFRERBB2FBP1TLR4TLR2 | |
| SCHEMBL16267490 | 0.82 | FBP1 (0.64) | EGFRERBB2FBP1TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199255-A1 | Reagents for improved cell-based assays | BECKMAN COULTER INC. (US) | 2006-09-07 | — | — | US | disclosed |