Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.39 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042452 | 0.84 | TYMS (0.41) | CYP2A6MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL19798970 | 0.83 | CYP2A6 (0.50) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL13296158 | 0.81 | CYP2A6 (0.41) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3771051 | 0.79 | ESR1 (0.33) | EPRS1SIRT2ESR2ESR1 | |
| SCHEMBL19862049 | 0.79 | SLC6A2 (0.42) | CYP2A6EPRS1BACE1ESR2ESR1 | |
| SCHEMBL5343236 | 0.79 | ESR2 (0.58) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL31444547 | 0.79 | ESR2 (0.58) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL56836 | 0.78 | CYP2A6 (0.57) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL20356031 | 0.77 | CYP2A6 (0.46) | CYP2A6ERN1MAPTKDM4EALDH1A1 | |
| SCHEMBL5752191 | 0.76 | CYP2A6 (0.48) | CYP2A6MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834559-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2023-12-05 | — | — | US | disclosed |
| CN-113527639-B | Method for preparing spinnable asphalt with high softening point from naphthalene and product thereof | 武汉科技大学 | 2022-08-02 | — | — | CN | disclosed |
| EP-4029904-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | Nanocore ApS (DK) | 2022-07-20 | — | — | EP | disclosed |
| CN-113527639-A | Method for preparing spinnable asphalt with high softening point from naphthalene and product thereof | 武汉科技大学 | 2021-10-22 | — | — | CN | disclosed |
| US-20210230381-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | NANOCORE APS (DK) | 2021-07-29 | — | — | US | disclosed |
| US-11028240-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2021-06-08 | — | — | US | disclosed |
| US-10301443-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2019-05-28 | — | — | US | disclosed |
| US-20180298154-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | NANOCORE APS (DK) | 2018-10-18 | — | — | US | disclosed |
| EP-3218427-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | NANOCORE APS (DK) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016078664-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | LUNDORF PEDERSEN MATERIALS APS (DK) | 2016-05-26 | — | — | WO | disclosed |
| CN-102442938-A | Fluorenyl-fluorene compound and application thereof | UNIV TSINGHUA | 2012-05-09 | — | — | CN | disclosed |
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| US-20060079533-A1 | Methods of treating alzheimer's disease | NIEMAN JAMES A | 2006-04-13 | — | — | US | disclosed |
| CN-1606540-A | Synthesis and use of dimethyl 1,5-naphthalenedicarboxylates and intermediates therefrom | BP CORP NORTH AMERICA INC (US) | 2005-04-13 | — | — | CN | disclosed |
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-6150526-A | Piperidine derivative having renin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-6051712-A | PREVENTION OF HIGH BLOOD PRESSURE AND CARDIAC INSUFFICIENCY, AS WELL AS GLAUCOMA, CARDIAC INFARCT, KIDNEY INSUFFICIENCY AND RESTENOSIS | HOFFMANN-LA ROCHE INC. (US) | 2000-04-18 | — | — | US | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |
| US-4675355-A | REACTIVE AMINE-CONTAINING NITROSO COMPOUND AND AN HALOGENATED ALKYLBENZENE TO IMPROVE GREEN STRENGTH; TIRES | BRIDGESTONE CORPORATION (JP) | 1987-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079533-A1 | Methods of treating alzheimer's disease | BACE1, PSEN1, PSEN2 | CYP2A6 3577/4885ERN1 3151/4885MAPT 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.