SCHEMBL56836

SCHEMBL56836

Brc1ccc2c(ccc3cc(Br)ccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.57
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 3/20 0.52
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
ERN1 O75460 1/20 0.52
BACE1 P56817 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
NCEH1 Q6PIU2 2/20 0.43
PLAU P00749 1/20 0.42
AHR P35869 2/20 0.42
NR4A2 P43354 1/20 0.42
METAP2 P50579 3/20 0.39
NOS1 P29475 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
CSNK2A1 P68400 1/20 0.39
DYRK1A Q13627 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12260028 0.97 CYP2A6 (0.55) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL646886 0.97 CYP2A6 (0.55) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL14353625 0.92 CYP2A6 (0.50) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL4354069 0.87 CYP2A6 (0.65) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL26834198 0.85 ALDH1A1 (0.78) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL15854449 0.85 ESR1 (0.48) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL25625349 0.85 CYP2A6 (0.52) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL12809576 0.85 CYP2A6 (0.44) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL1461934 0.85 ERN1 (0.52) CYP2A6MEN1KMT2AMAPTALDH1A1
SCHEMBL18646836 0.85 HPRT1 (0.64) CYP2A6MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306704-A Triazine aromatic group-containing condensed ring electron transport material 安庆飞凯新材料有限公司 2025-01-14 CN claimed
CN-119081108-A Bipolar organic positive electrode material, and preparation method and application thereof 西南大学 2024-12-06 CN claimed
CN-116891566-A Fluorescence enhanced polymer probe for rapidly detecting Cr (III), and synthesis method and application thereof 武汉工程大学 2023-10-17 CN claimed
CN-116143798-B Diphenylamine organic matter based on phenanthrenequinone derivative 云南大学 2023-07-14 CN claimed
CN-116143798-A Diphenylamine organic matter based on phenanthrenequinone derivative 云南大学 2023-05-23 CN claimed
CN-115521441-A Conjugated microporous polymer and preparation method and application thereof 东华理工大学 2022-12-27 CN claimed
EP-3287506-B1 PHENANTHRENE DERIVATIVES MERCK PATENT GMBH (DE) 2020-02-26 EP claimed
CN-104650118-B Preparation method and application of derivative by taking dibenzofuran as skeleton core 吉林奥来德光电材料股份有限公司 2017-01-11 CN claimed
CN-104650118-A Preparation method and application of derivative by taking dibenzofuran as skeleton core JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2015-05-27 CN claimed
CN-104629719-A Fluorene derivatives and applications thereof in electroluminescent devices JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2015-05-20 CN claimed
EP-4638547-A1 AROMATIC POLYMER, PROCESS FOR PRODUCING A POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-10-29 EP disclosed
EP-4407013-B1 PHOTOACTIVE MACROMOLECULES AND USES THEREOF BECKMAN COULTER INC (US) 2025-09-17 EP disclosed
EP-4610656-A2 PHOTOACTIVE MACROMOLECULES AND USES THEREOF Beckman Coulter, Inc. (US) 2025-09-03 EP disclosed
US-12312437-B2 Photoactive macromolecules and uses thereof BECKMAN COULTER, INC. (US) 2025-05-27 US disclosed
WO-2025064842-A1 DIHYDROPHENANTHRENE (DHP) BRIDGED DYES FOR USE IN FLOW CYTOMETRY BECKMAN COULTER, INC. (US) 2025-03-27 WO disclosed
US-20070075635-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-04-05 US disclosed
US-20070029927-A1 AROMATIC AMINE DERIVATIVES AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-02-08 US disclosed
WO-2006047119-A1 ARYLCARBAZ AS HOSTS IN PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2006-05-04 WO disclosed
US-20060088728-A1 Arylcarbazoles as hosts in PHOLEDs KWONG RAYMOND 2006-04-27 US disclosed
US-3988369-A Process and reactant for halogenating organic compounds PEARSON DONALD E 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070029927-A1 AROMATIC AMINE DERIVATIVES AND ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, MAOB CYP2A6 2154/4885MEN1 1697/4885KMT2A 249/4885
US-20060088728-A1 Arylcarbazoles as hosts in PHOLEDs CYCS, TYR, OXA1L CYP2A6 1760/4885MEN1 4258/4885KMT2A 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.