Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960982 | 0.82 | GAA (0.42) | GAACD44CYP3A4TSHRNPC1 | |
| SCHEMBL14143885 | 0.78 | HPGD (0.48) | CYP3A4TSHRNPC1MEN1USP2 | |
| SCHEMBL9017622 | 0.75 | POLB (0.35) | GAACD44CYP3A4LMNACYP1A2 | |
| SCHEMBL3668733 | 0.73 | GAA (0.42) | GAACD44CYP3A4TSHRNPC1 | |
| SCHEMBL3031653 | 0.72 | GAA (0.37) | GAACD44CYP3A4TSHRNPC1 | |
| SCHEMBL31532254 | 0.72 | GAA (0.37) | GAACD44CYP3A4TSHRNPC1 | |
| SCHEMBL21052048 | 0.71 | CYP3A4 (0.39) | GAACD44CYP3A4HTR1ASLC6A2 | |
| SCHEMBL31676788 | 0.71 | CYP3A4 (0.39) | GAACD44CYP3A4HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL8075443 | 0.71 | GAA (0.36) | GAACD44CYP3A4TSHRNPC1 | |
| SCHEMBL6162367 | 0.70 | CYP3A4 (0.37) | GAACD44CYP3A4TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748540-B2 | Compositions comprising solvated aromatic amines and methods for the preparation thereof | Crosslink Technology, Inc | 2014-06-10 | — | — | US | claimed |
| WO-2010118527-A1 | COMPOSITIONS COMPRISING SOLVATED AROMATIC AMINES AND METHODS FOR THE PREPARATION THEREOF | CROSSLINK TECHNOLOGY INC. (CA) | 2010-10-21 | — | — | WO | claimed |
| US-8748540-B2 | Compositions comprising solvated aromatic amines and methods for the preparation thereof | Crosslink Technology, Inc | 2014-06-10 | — | — | US | disclosed |
| US-20120040094-A1 | Compositions Comprising Solvated Aromatic Amines and Methods for the Preparation Thereof | CROSSLINK TECHNOLOGY, INC. (CA) | 2012-02-16 | — | — | US | disclosed |
| WO-2010118527-A1 | COMPOSITIONS COMPRISING SOLVATED AROMATIC AMINES AND METHODS FOR THE PREPARATION THEREOF | CROSSLINK TECHNOLOGY INC. (CA) | 2010-10-21 | — | — | WO | disclosed |