SCHEMBL8960982

SCHEMBL8960982

CCc1c(N)cc(Cl)c(N)c1CC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
CD44 P16070 1/20 0.39
CYP3A4 P08684 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
NPC1 O15118 1/20 0.30
TSHR P16473 3/20 0.30
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRK1 P41145 1/20 0.30
SLC6A3 Q01959 1/20 0.30
TP53 P04637 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL604293 0.82 GAA (0.42) GAACD44CYP3A4ALDH1A1NPC1
SCHEMBL3668733 0.82 GAA (0.42) GAACD44CYP3A4ALDH1A1NPC1
SCHEMBL8153959 0.74 HTT (0.42) ALDH1A1
SCHEMBL29568662 0.74 ALDH1A1 (0.40) CD44CYP3A4ALDH1A1TSHRTP53
SCHEMBL8523312 0.74 ALDH1A1 (0.40) CD44CYP3A4ALDH1A1TSHRTP53
SCHEMBL24603696 0.74 CYP3A4 (0.36) CYP3A4ALDH1A1CA1CA2CA9
SCHEMBL9362431 0.74 ALDH1A1 (0.36) CYP3A4ALDH1A1
SCHEMBL669350 0.73 CYP3A4 (0.38) GAACD44CYP3A4ALDH1A1CA1
Hydrochloric Acid SCHEMBL4771781 0.73 HTT (0.41) ALDH1A1
SCHEMBL9361882 0.71 TAAR1 (0.34) GAACYP3A4ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240371-B2 Method of processing lightsensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1996-01-31 EP disclosed
US-5082765-A Developers containing aromatic primary amines in combination w ith sensitizers KONICA CORPORATION (JP) 1992-01-21 US disclosed
EP-0240371-A2 Method of processing lightsensitive silver halide photographic material KONICA CORPORATION (JP) 1987-10-07 EP disclosed
EP-0073145-A1 A phenol cyan coupler for silver halide color photographic material KONICA CORPORATION (JP) 1983-03-02 EP disclosed