Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961346 | 0.89 | BACE1 (0.57) | BACE1BACE2CTSD | |
| SCHEMBL6043858 | 0.81 | BACE1 (0.62) | BACE1BACE2CTSD | |
| SCHEMBL8320359 | 0.78 | NTRK2 (0.51) | BACE1BACE2 | |
| SCHEMBL5363946 | 0.78 | BACE1 (0.74) | BACE1BACE2CTSD | |
| SCHEMBL6043864 | 0.78 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL3350500 | 0.77 | BACE1 (0.77) | BACE1BACE2CTSD | |
| SCHEMBL3350491 | 0.77 | BACE1 (0.77) | BACE1BACE2CTSD | |
| SCHEMBL4891462 | 0.76 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL3351740 | 0.76 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL8364786 | 0.76 | BACE1 (0.71) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100196-A1 | Substituted amines for the treatment of alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100196-A1 | Substituted amines for the treatment of alzheimer's disease | BACE1, APP, BACE2 | BACE1 1/4885BACE2 3/4885CTSD 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.