Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324368 | 0.80 | BACE1 (0.45) | NTRK2F2BACE1BACE2 | |
| SCHEMBL6043869 | 0.78 | BACE1 (0.57) | BACE1BACE2 | |
| SCHEMBL18902272 | 0.76 | L3MBTL1 (0.71) | KDM4EPOLBL3MBTL1SMN1; SMN2NAAA | |
| SCHEMBL7067047 | 0.76 | NTRK2 (0.56) | NTRK2L3MBTL1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL17688583 | 0.76 | NTRK2 (0.56) | NTRK2L3MBTL1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL14141210 | 0.76 | TP53 (0.50) | F2SMN1; SMN2BACE1BACE2 | |
| SCHEMBL17789002 | 0.76 | SMN1; SMN2 (0.55) | L3MBTL1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL6139506 | 0.75 | MLYCD (0.44) | F2SMN1; SMN2BACE1BACE2 | |
| SCHEMBL8321271 | 0.74 | BACE1 (0.42) | NTRK2KDM4EPOLBBACE1BACE2 | |
| SCHEMBL8361174 | 0.74 | BACE1 (0.46) | NTRK2BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |