SCHEMBL6043884

SCHEMBL6043884

[CH2]CC(N)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958399 0.72
SCHEMBL6042956 0.68
SCHEMBL608733 0.67
SCHEMBL3067654 0.67
SCHEMBL4384900 0.67
SCHEMBL4969205 0.67
SCHEMBL1512939 0.67
Thiourea SCHEMBL11869817 0.64
Thiourea SCHEMBL110431 0.64
SCHEMBL2002945 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105968090-A Carboxamide compounds and their use as calpain inhibitors ABBVIE 公司 2016-09-28 CN disclosed
CN-102333766-A Carboxamide compounds and their use as calpain inhibitors ABBOTT GMBH & CO KG 2012-01-25 CN disclosed
US-20060089355-A1 Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides ELAN PHARMACEUTICALS, INC. 2006-04-27 US disclosed
CN-1147298-C Prevention and curing agent for c attenuation living vaccine 卫材株式会社 2004-04-28 CN disclosed
WO-2003103652-A1 METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed
EP-0741694-B1 PHENYL ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND AGENTS CONTAINING THEM BASF AG (DE) 2003-04-02 EP disclosed
US-6509379-B1 Variables are as disclosed herein, their salts, processes and intermediates for their preparation, and their use for controlling harmful fungi and animal pests. BASF AKTIENGESELLSCHAFT (DE) 2003-01-21 US disclosed
US-RE37873-E1 Phenylacetic acid derivatives, preparation thereof and intermediates therefor, and compositions containing them BASF AKTIENGESELLSCHAFT (DE) 2002-10-08 US disclosed
EP-0842144-B1 PHENYL ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS PARASITICIDES AND FUNGICIDES BASF AG (DE) 2001-10-31 EP disclosed
EP-0873305-B1 AZINOOXIMETHERS, PROCESSES AND INTERMEDIATE PRODUCTS FOR MANUFACTURING SAME, AND THE USES THEREOF IN COMBATING HARMFUL FUNGI AND PESTS BASF AG (DE) 2001-03-28 EP disclosed
CN-1143361-A Phenylacetic acid derivatives, their preparation and intermediates, and compositions containing them BASF AG (DE) 1997-02-19 CN disclosed
CN-1137895-A Prevention and curing agent for c attenuation living vaccine EISAI CO LTD (JP) 1996-12-18 CN disclosed
CN-1136556-A Aromatic group substituted W-amino alkyl amide and alkyl amide CIBA GEIGY CO LTD (CH) 1996-11-27 CN disclosed
EP-0716077-A1 Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors CIBA-GEIGY AG (CH) 1996-06-12 EP disclosed
CN-1069882-A The Compounds and methods for that suppresses HIV and correlated virus MEDIVIR AB (CH) 1993-03-17 CN disclosed
US-4439433-A CEPHALOSPORIN ANTIBIOTICS ROUSSEL UCLAF (FR) 1984-03-27 US disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-4191613-A BONDED TO HAPTEN SYVA COMPANY (US) 1980-03-04 US disclosed
US-4065354-A HAPTENS SYVA COMPANY (US) 1977-12-27 US disclosed