Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 11/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797593 | 0.89 | MAPT (0.73) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL581227 | 0.88 | HCAR3 (0.73) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL6043949 | 0.87 | HCAR3 (1.00) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL2688335 | 0.85 | HCAR3 (1.00) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL22126379 | 0.85 | HCAR3 (0.70) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL27858164 | 0.84 | HCAR3 (0.69) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL6044176 | 0.83 | HCAR3 (1.00) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL24032 | 0.83 | HCAR3 (1.00) | HCAR3MAPTALDH1A1KMT2A | |
| SCHEMBL28183325 | 0.82 | HCAR3 (0.86) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL6044024 | 0.82 | HCAR3 (1.00) | HCAR3MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | GCGR, GPR119, HMGCR | HCAR3 85/4885MAPT 3284/4885ALDH1A1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.