⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531718 | 0.76 | — | — | |
| SCHEMBL14933753 | 0.74 | — | — | |
| SCHEMBL8828271 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL24278947 | 0.72 | — | — | |
| SCHEMBL7246710 | 0.72 | — | — | |
| Ethylamine SCHEMBL11779518 | 0.72 | ALOX15 (0.30) | — | |
| SCHEMBL2371280 | 0.72 | — | — | |
| SCHEMBL1071324 | 0.67 | CYP1A2 (0.39) | — | |
| SCHEMBL13983442 | 0.67 | — | — | |
| Methylamine SCHEMBL10877320 | 0.67 | ALOX15 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060035823-A1 | Isolated fragments of p62 nucleoporin and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-16 | — | — | US | disclosed |