Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681360 | 0.97 | ALPL (0.38) | ALPLPOLBALPGALDH1A1LMNA | |
| Acetic Acid SCHEMBL3682289 | 0.92 | ALPL (0.35) | ALPLPOLBALPGALDH1A1CHRM1 | |
| Acetic Acid SCHEMBL3682298 | 0.88 | ALPL (0.41) | ALPLPOLBALPGCHRM1AKR1A1 | |
| Trifluoroacetic Acid SCHEMBL3684531 | 0.84 | ALPL (0.35) | ALPLPOLBALPG | |
| Trifluoroacetic Acid SCHEMBL3684537 | 0.81 | ALPL (0.37) | ALPLPOLBALPG | |
| SCHEMBL5538444 | 0.77 | CHRM1 (0.50) | ALPLPOLBALPGCHRM1AKR1A1 | |
| SCHEMBL15610744 | 0.77 | CHRM1 (0.33) | ALPLPOLBALPGCHRM1AKR1A1 | |
| SCHEMBL7505468 | 0.76 | OR51E2 (0.39) | ALPLPOLBALPGALDH1A1LMNA | |
| SCHEMBL172177 | 0.76 | OR51E2 (0.39) | ALPLPOLBALPGALDH1A1LMNA | |
| SCHEMBL1427298 | 0.74 | POLB (0.50) | ALPLPOLBALPGCA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119465164-A | Corrosion inhibitor for improving corrosion resistance of white copper | 有研工程技术研究院有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-113209160-A | Oral ulcer gel and preparation method thereof | 云南昭药健康产业有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113209160-A | Oral ulcer gel and preparation method thereof | 云南昭药健康产业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113209160-A | Oral ulcer gel and preparation method thereof | 云南昭药健康产业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-7109377-B2 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-19 | — | — | US | disclosed |
| US-6448443-B1 | GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-09-10 | — | — | US | disclosed |