⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769966 | 0.71 | — | — | |
| SCHEMBL228107 | 0.71 | — | — | |
| SCHEMBL223825 | 0.64 | — | — | |
| SCHEMBL8770001 | 0.64 | — | — | |
| SCHEMBL9021062 | 0.61 | — | — | |
| SCHEMBL3462993 | 0.60 | — | — | |
| SCHEMBL15941914 | 0.60 | — | — | |
| SCHEMBL6721323 | 0.58 | — | — | |
| SCHEMBL147868 | 0.58 | — | — | |
| SCHEMBL4592860 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259779-B2 | Structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity | WAYNE STATE UNIVERSITY (US) | 2019-04-16 | — | — | US | claimed |
| EP-3079475-A2 | GLUCOCORTICOID INHIBITORS FOR TREATMENT OF PROSTATE CANCER | Sloan-kettering Institute For Cancer Research (US) | 2016-10-19 | — | — | EP | claimed |
| WO-2015089338-A2 | GLUCOCORTICOID INHIBITORS FOR TREATMENT OF PROSTATE CANCER | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-06-18 | — | — | WO | claimed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239775-A1 | FXR REGULATOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | BEIJING BEST PATHWAY MANAGEMENT CONSULTING CENTER (LIMITED PARTNERSHIP) (CN) | 2024-07-18 | — | — | US | disclosed |
| US-12037329-B2 | SphK inhibitors and methods of making and using same | WASHINGTON UNIVERSITY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118344348-A | Heterocyclic substituted quinazoline and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240226313-A1 | CEACAM5 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | SEAGEN INC. | 2024-07-11 | — | — | US | disclosed |
| EP-0496106-A1 | Stable agrochemical compositions | Takeda Chemical Industries, Ltd. (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0445731-A1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER-LAMBERT COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4855449-A | Prostacyclin (PGI2) analogues | SHIONOGI & CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| US-4820836-A | ANTICOAGULANTS, ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0251905-A2 | Esters of alginic acid | FIDIA S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0240890-A2 | Prostacyclin (PGI2) analogues | SHIONOGI & CO., LTD. (JP) | 1987-10-14 | — | — | EP | disclosed |
| US-4675045-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4272543-A | Pharmacologically active 4,5-diaryl-2-substituted-imidazoles | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-06-09 | — | — | US | disclosed |
| US-4020178-A | 1,4-Dihydropyridine esters used as coronary dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-26 | — | — | US | disclosed |