Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045603 | 0.90 | LMNA (0.44) | CYP3A4HSD17B10DRD2DRD4DRD3 | |
| SCHEMBL6045710 | 0.87 | SMN1; SMN2 (0.44) | CYP3A4HSD17B10DRD2DRD4DRD3 | |
| SCHEMBL6045642 | 0.85 | BACE1 (0.35) | KMT2ASIGMAR1 | |
| SCHEMBL9372381 | 0.81 | OPRL1 (0.49) | CYP3A4HSD17B10DRD2DRD4DRD3 | |
| SCHEMBL6045466 | 0.81 | NPFFR1 (0.46) | CYP3A4HSD17B10NPFFR1NPFFR2ALDH1A1 | |
| SCHEMBL6045686 | 0.77 | CYP3A4 (0.43) | CYP3A4HSD17B10DRD2DRD4DRD3 | |
| SCHEMBL30122291 | 0.76 | OPRL1 (0.58) | CYP3A4HSD17B10NPFFR1NPFFR2DRD2 | |
| SCHEMBL6045663 | 0.74 | LMNA (0.47) | CYP3A4HSD17B10NPFFR1NPFFR2ALDH1A1 | |
| SCHEMBL6045724 | 0.73 | NPFFR1 (0.44) | CYP3A4HSD17B10NPFFR1NPFFR2ALDH1A1 | |
| SCHEMBL6045421 | 0.73 | CYP2D6 (0.44) | CYP3A4HSD17B10ALDH1A1CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | CYP3A4 4753/4885HSD17B10 3738/4885NPFFR1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.