Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045724 | 0.82 | NPFFR1 (0.44) | LMNAPOLBNPFFR1NPFFR2CYP3A4 | |
| SCHEMBL6045466 | 0.81 | NPFFR1 (0.46) | LMNAPOLBNPFFR1NPFFR2CYP3A4 | |
| SCHEMBL30122291 | 0.76 | OPRL1 (0.58) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 | |
| SCHEMBL6045515 | 0.75 | NPFFR1 (0.46) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 | |
| SCHEMBL6045725 | 0.74 | NPFFR1 (0.43) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 | |
| SCHEMBL6045533 | 0.74 | CYP3A4 (0.45) | LMNAPOLBNPFFR1NPFFR2CYP3A4 | |
| SCHEMBL9372890 | 0.74 | NPFFR1 (0.45) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 | |
| SCHEMBL6045459 | 0.74 | NPFFR1 (0.45) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 | |
| SCHEMBL7468609 | 0.73 | CYP2D6 (0.45) | LMNAPOLBCYP3A4OPRL1ALDH1A1 | |
| SCHEMBL27296558 | 0.72 | NPFFR1 (0.46) | POLBNPFFR1NPFFR2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | LMNA 1044/4885POLB 4597/4885NPFFR1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.