Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homovanillic Acid SCHEMBL10535396 | 0.87 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL30337229 | 0.87 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL8792 | 0.87 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL27603186 | 0.85 | GAA (0.97) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL18138956 | 0.81 | GAA (0.88) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Phenylacetic Acid SCHEMBL4318843 | 0.79 | GAA (0.63) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL27563007 | 0.79 | GAA (0.72) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL18162754 | 0.79 | GAA (0.72) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Guaiacol SCHEMBL27757080 | 0.79 | TSHR (0.63) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL31722795 | 0.79 | GAA (0.82) | GAATSHRNFKB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060263784-A1 | Method for the diagnosis/prognosis of neuroblastoma | CENTRE LEON-BERARD (FR) | 2006-11-23 | — | — | US | disclosed |