Homovanillic Acid

Homovanillic Acid

SCHEMBL8792

COc1cc(CC(=O)O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 1.00
TSHR P16473 3/20 1.00
NFKB1 P19838 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 0.61
KDM4E B2RXH2 1/20 0.61
RGS12 O14924 1/20 0.61
POLB P06746 1/20 0.61
MAPT P10636 1/20 0.61
HPGD P15428 1/20 0.61
APEX1 P27695 1/20 0.61
THPO P40225 1/20 0.61
BLM P54132 1/20 0.61
GNAI1 P63096 1/20 0.61
PMP22 Q01453 1/20 0.61
HIF1A Q16665 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CA5A P35218 1/20 0.60
ALOX5 P09917 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homovanillic Acid SCHEMBL30337229 1.00 GAA (1.00) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL10535396 1.00 GAA (1.00) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL27603186 0.98 GAA (0.97) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL18138956 0.94 GAA (0.88) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL28834465 0.91 GAA (0.82) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL31722795 0.91 GAA (0.82) GAATSHRNFKB1TDP1ALDH1A1
SCHEMBL1596139 0.88 GAA (0.78) GAATSHRNFKB1TDP1ALDH1A1
SCHEMBL7114863 0.87 TSHR (0.77) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL6045796 0.87 GAA (0.76) GAATSHRNFKB1TDP1ALDH1A1
Homovanillic Acid SCHEMBL9796291 0.87 TSHR (0.76) GAATSHRNFKB1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9611 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146299-A1 Electrochemical Genosensor Based on Target-Triggered DNAzyme Activity THE PENN STATE RESEARCH FOUNDATION (US) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260091037-A1 METHODS FOR INCREASING SEPIAPTERIN PLASMA EXPOSURE PTC THERAPEUTICS MP INC (US) 2026-04-02 US claimed
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US claimed
US-12575601-B2 Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols MAGI'S LAB SRL (IT) 2026-03-17 US claimed
EP-3801534-B1 TREATMENT OF PHENYLKETONURIA WITH SEPIAPTERIN PTC THERAPEUTICS MP INC (US) 2026-02-18 EP claimed
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250382424-A1 PROCESS FOR MODIFYING THE MELTING CHARACTERISTICS OF A LIGNIN TANOVIS AG (CH) 2025-12-18 US claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
US-4367285-A Assaying lipid peroxide in lipid compositions TOYO JOZO COMPANY, LTD. (JP) 1983-01-04 US claimed
US-4362510-A ESTER OF VANILLIC ACID, METAL OXIDE OR HYDROXIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1982-12-07 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
US-4259947-A ISOTOPICALLY LABELED COMPOUNDS KOBRINSKY PETER C 1981-04-07 US claimed
US-4246342-A BACTERIAL BIOSYNTHESIS, USE IN DETERMINATION OF PYRUVIC ACID TOYO JOZO KABUSHIKI KAISHA (JP) 1981-01-20 US claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US claimed