Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homovanillic Acid SCHEMBL8792 | 1.00 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL10535396 | 1.00 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL27603186 | 0.98 | GAA (0.97) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL18138956 | 0.94 | GAA (0.88) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL28834465 | 0.91 | GAA (0.82) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL31722795 | 0.91 | GAA (0.82) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL1596139 | 0.88 | GAA (0.78) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL7114863 | 0.87 | TSHR (0.77) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL6045796 | 0.87 | GAA (0.76) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL9796291 | 0.87 | TSHR (0.76) | GAATSHRNFKB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115997015-A | Donor T cells with kill switch | 美国杰特贝林生物制品有限公司 | 2023-04-21 | — | — | CN | disclosed |