Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 4/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046282 | 0.98 | SLC6A11 (0.46) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL6046270 | 0.98 | SLC6A11 (0.46) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL1764229 | 0.95 | SLC6A11 (0.48) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL16197752 | 0.86 | KIF11 (0.50) | SLC6A11SLC6A1KIF11KCNH2MEN1 | |
| SCHEMBL5819858 | 0.85 | KIF11 (0.47) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL16353449 | 0.85 | KIF11 (0.61) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL5819943 | 0.85 | KIF11 (0.47) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL8860350 | 0.85 | SLC6A11 (0.47) | SLC6A11SLC6A1KIF11KCNH2MEN1 | |
| SCHEMBL18413416 | 0.85 | KIF11 (0.47) | SLC6A11SLC6A1KIF11KCNH2TK1 | |
| SCHEMBL28577719 | 0.84 | PDE4B (0.52) | SLC6A11SLC6A1KIF11KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060193869-A1 | Methods and compositions for induction or promotion of immune tolerance | DYNAVAX TECHNOLOGIES CORPORATION | 2006-08-31 | — | — | US | disclosed |