Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | BLVRB | P30043 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046301 | 1.00 | MAPT (0.65) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL28197525 | 0.79 | MEN1 (0.66) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28287460 | 0.76 | MAPT (0.66) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL27973104 | 0.76 | MAPT (0.66) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL30620152 | 0.74 | MAPT (0.63) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL11429873 | 0.72 | MAPT (0.64) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL27280964 | 0.72 | MAPT (0.60) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL13219022 | 0.71 | MAPT (0.59) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL27280962 | 0.71 | MAPT (0.52) | MAPTNPC1HTTMEN1KMT2A | |
| SCHEMBL22995573 | 0.70 | MEN1 (0.68) | MAPTNPC1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | claimed |
| WO-2006124003-A1 | COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-11-23 | — | — | WO | claimed |
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | disclosed |
| WO-2006124003-A1 | COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-11-23 | — | — | WO | disclosed |