Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609661 | 0.83 | ADORA3 (0.54) | ADORA3ADORA2AROCK2ACHENFATC1 | |
| SCHEMBL3886263 | 0.83 | BCHE (0.52) | MAPTBCHEACHEESR1 | |
| SCHEMBL17109975 | 0.81 | ADORA3 (0.51) | ADORA3ADORA2AROCK2ACHENFATC1 | |
| SCHEMBL17940518 | 0.79 | ROCK2 (0.53) | ADORA3ADORA2AROCK2MAPTACHE | |
| SCHEMBL24276814 | 0.78 | ADORA3 (0.41) | ADORA3ADORA2AROCK2MAPTBCHE | |
| SCHEMBL16345042 | 0.78 | ROCK2 (0.62) | ADORA3ADORA2AROCK2 | |
| SCHEMBL16102674 | 0.77 | MAPT (0.37) | ADORA3ADORA2AROCK2MAPTESR1 | |
| SCHEMBL1921708 | 0.77 | HASPIN (0.61) | ADORA3ADORA2AROCK2MAPTBCHE | |
| SCHEMBL2718934 | 0.76 | ADORA3 (0.45) | ADORA3ADORA2AROCK2BCHEACHE | |
| SCHEMBL2628358 | 0.76 | ADORA3 (0.49) | ADORA3ADORA2AROCK2ACHENFATC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | claimed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | claimed |
| WO-2006124003-A1 | COMPOSITE MALDI MATRIX MATERIAL AND METHODS OF USING IT AND KITS THEREOF IN MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-11-23 | — | — | WO | disclosed |