Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046651 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAMAPK1HTT | |
| SCHEMBL6943834 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTGAANR1D1L3MBTL1 | |
| SCHEMBL9728624 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTGAANR1D1L3MBTL1 | |
| SCHEMBL5723865 | 0.82 | ALDH1A1 (0.65) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL14535782 | 0.82 | SYK (0.52) | ALDH1A1MAPTL3MBTL1MAPK1HTT | |
| SCHEMBL5723717 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAHTTPPARG | |
| SCHEMBL2299040 | 0.80 | IDO1 (0.58) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL3176366 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAANR1D1L3MBTL1 | |
| SCHEMBL14128576 | 0.78 | CHRM2 (0.49) | ALDH1A1MAPTGAANR1D1PPARG | |
| SCHEMBL3558360 | 0.78 | PPARG (0.49) | ALDH1A1MAPTGAANR1D1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | LABORATOIRES SERONO SA (CH) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | APP, APBA1, IAPP | ALDH1A1 4161/4885MAPT 302/4885GAA 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.