Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555636 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL6943834 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL27787118 | 0.85 | GAA (0.60) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL5723865 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL9344653 | 0.84 | LMNA (0.57) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL10389201 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL6046651 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAMAPK1RAB9A | |
| SCHEMBL6046662 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL9044759 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL10389171 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |