Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | CDC25B | P30305 | 10/20 | 0.49 |
| ▸ | APAF1 | O14727 | 6/20 | 0.49 |
| ▸ | CASP3 | P42574 | 5/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | UBE2I | P63279 | 2/20 | 0.49 |
| ▸ | GALK1 | P51570 | 1/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303909 | 0.81 | LOXL2 (1.00) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL1720643 | 0.81 | LOXL2 (0.68) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL30249827 | 0.81 | LOXL2 (1.00) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL7452968 | 0.81 | LOXL2 (0.68) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL11665605 | 0.80 | LOXL2 (0.62) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL2599466 | 0.78 | LOXL2 (0.74) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL7106470 | 0.78 | PARP1 (0.65) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL6603861 | 0.77 | LOXL2 (0.62) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL6645515 | 0.77 | TNKS (0.62) | LOXL2KDM4EGAACDC25BAPAF1 | |
| SCHEMBL1687342 | 0.76 | KDM4E (0.60) | LOXL2KDM4EGAACDC25BAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | claimed |
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | disclosed |