Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046910 | 1.00 | MAPT (0.46) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL9638174 | 0.96 | PTGS2 (0.45) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL9766280 | 0.96 | MAPT (0.45) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL9551059 | 0.93 | MAPT (0.52) | MAPTMMP14MEN1KMT2AATM | |
| SCHEMBL9650790 | 0.91 | MAPT (0.48) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL9650794 | 0.91 | MAPT (0.48) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL9655690 | 0.90 | PPARG (0.46) | MAPTPTGS2PTGS1NPC1RAB9A | |
| SCHEMBL9766276 | 0.89 | BACE1 (0.43) | MAPTMMP14PTGS2PTGS1MEN1 | |
| SCHEMBL6046907 | 0.88 | PTGS2 (0.44) | MAPTMMP14PTGS2PTGS1NPC1 | |
| SCHEMBL6046908 | 0.88 | PTGS2 (0.44) | MAPTMMP14PTGS2PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166033-A1 | Polymerizable, luminescent compounds and mixtures, luminescent polymer materials and their use | MERCK PATENT GMBH (DE) | 2006-07-27 | — | — | US | disclosed |