Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046909 | 0.89 | MAPT (0.46) | MAPTKMT2APTGS2PTGS1MMP14 | |
| SCHEMBL6046910 | 0.89 | MAPT (0.46) | MAPTKMT2APTGS2PTGS1MMP14 | |
| SCHEMBL9766280 | 0.85 | MAPT (0.45) | MAPTMAPK1KMT2APTGS2PTGS1 | |
| SCHEMBL9638174 | 0.85 | PTGS2 (0.45) | MAPTALDH1A1KMT2APTGS2PTGS1 | |
| SCHEMBL9551059 | 0.82 | MAPT (0.52) | MAPTALDH1A1TDP1MAPK1KMT2A | |
| SCHEMBL9650790 | 0.81 | MAPT (0.48) | MAPTALDH1A1TDP1MAPK1KMT2A | |
| SCHEMBL9650794 | 0.81 | MAPT (0.48) | MAPTALDH1A1TDP1MAPK1KMT2A | |
| SCHEMBL9655690 | 0.80 | PPARG (0.46) | MAPTALDH1A1KMT2AHTTPTGS2 | |
| SCHEMBL6046907 | 0.78 | PTGS2 (0.44) | MAPTALDH1A1KMT2APTGS2PTGS1 | |
| SCHEMBL6046908 | 0.78 | PTGS2 (0.44) | MAPTALDH1A1KMT2APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003683-A1 | ACRYLIC COPOLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORP (US) | 1991-03-21 | — | — | WO | disclosed |