SCHEMBL6046944

SCHEMBL6046944

CC(C)C(=O)c1nc2nc(N)[nH]c(=O)c2n1CC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLA2G10 O15496 1/20 0.32
PLA2G5 P39877 1/20 0.32
MAPK1 P28482 1/20 0.32
ELANE P08246 1/20 0.32
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31
JAK3 P52333 1/20 0.31
PNP P00491 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046932 0.83 PNP (0.42) ALDH1A1MAPK1PNP
SCHEMBL8177048 0.62 MAPT (0.40) KDM4EALDH1A1MAPK1PNP
SCHEMBL2435848 0.62 PNP (0.43) ALDH1A1MAPK1PNP
SCHEMBL20967569 0.61 ALDH1A1 (0.49) KDM4EALDH1A1PLA2G10PLA2G5JAK2
SCHEMBL7262837 0.61 HPGD (0.46) ALDH1A1
SCHEMBL453203 0.60 PNP (0.58) KDM4EALDH1A1PNP
SCHEMBL7812589 0.59 PNP (0.53) PNP
SCHEMBL3581217 0.58 KDM4E (0.41) KDM4EALDH1A1PLA2G10PLA2G5JAK2
SCHEMBL5123617 0.58 KDM4E (0.41) KDM4EALDH1A1PLA2G10PLA2G5ELANE
SCHEMBL23392711 0.57 TYMS (0.37) KDM4EALDH1A1MAPK1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105525-B1 A PROCESS FOR PREPARING PEPTIDE NUCLEIC ACID PROBE USING POLYMERIC PHOTOACID GENERATOR SAMSUNG ELECTRONICS CO LTD (KR) 2006-11-02 EP disclosed
US-6660479-B2 Derivatizing surface of a solid matrix and attaching linker with acid- labile protecting group on solid matrix; coating solid matrix with polymeric photoacid generator(PAG); exposing solid matrix thus coated to light to generate acid; reacting SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-12-09 US disclosed
US-20020122874-A1 Process for preparing peptide nucleic acid probe using polymeric photoacid generator SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-09-05 US disclosed
US-6359125-B1 DERIVATIZING SURFACE OF SOLID MATRIX WITH AMINOALKYLOXYSILANE AND ATTACHING LINKER WITH ACID-LABILE PROTECTING GROUP TO AMINE GROUP ON MATRIX, COATING MATRIX WITH POLYMERIC PHOTOACID GENERATOR, EXPOSING TO LIGHT, ATTACHING PEPTIDE NUCLEIC ACID SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-03-19 US disclosed