Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177048 | 0.84 | MAPT (0.40) | PNPKMT2AMEN1MAPK1MAPT | |
| SCHEMBL2434143 | 0.82 | PNP (0.57) | PNPKMT2AMEN1HBBMAPK1 | |
| SCHEMBL7816005 | 0.72 | TYMS (0.56) | PNPKMT2AMEN1 | |
| SCHEMBL7806221 | 0.71 | TYMS (0.59) | PNPKMT2AMEN1MAPTHSD17B10 | |
| SCHEMBL8781905 | 0.71 | PNP (0.55) | PNPKMT2AMEN1HBBMAPK1 | |
| SCHEMBL9566544 | 0.71 | PNP (0.71) | PNPKMT2AMEN1HBBMAPK1 | |
| SCHEMBL7814355 | 0.68 | MEN1 (0.76) | PNPKMT2AMEN1HBBMAPK1 | |
| SCHEMBL7814363 | 0.68 | HPRT1 (0.55) | PNPKMT2AMEN1HBBMAPK1 | |
| SCHEMBL8165565 | 0.68 | PNP (0.51) | PNPKMT2AMEN1HBBTSHR | |
| SCHEMBL7813638 | 0.68 | TYMS (0.60) | PNPKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114336-A1 | PROCESS FOR THE ISOLATION OF GANCICLOVIR INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2011-09-22 | — | — | WO | disclosed |
| EP-0862570-B1 | PROCESS FOR THE PREPARATION OF 9- (2-HYDROXYETHOXY)METHYL]GUANINE | CLARIANT LSM ITALIA SPA (IT) | 2001-03-21 | — | — | EP | disclosed |
| EP-0976751-A1 | A process for the isomerisation of an N-7 isomer into an N-9 isomer useful in the synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976751-A1 | A process for the isomerisation of an N-7 isomer into an N-9 isomer useful in the synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 2000-02-02 | — | — | EP | disclosed |
| EP-0862570-A1 | PROCESS FOR THE PREPARATION OF 9- (2-HYDROXYETHOXY)METHYL]GUANINE | ARCHIMICA S.P.A. (IT) | 1998-09-09 | — | — | EP | disclosed |
| EP-0806425-A1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997018211-A1 | PROCESS FOR THE PREPARATION OF 9-[(2-HYDROXYETHOXY)METHYL]GUANINE | ARCHIMICA S.P.A. (IT) | 1997-05-22 | — | — | WO | disclosed |