Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9183635 | 1.00 | CA5A (0.55) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL28099578 | 1.00 | CA5A (0.55) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL3469103 | 1.00 | CA5A (0.55) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL16770295 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL20184171 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL7871314 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL3789081 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL4658502 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL4482457 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 | |
| Phosphoric Acid SCHEMBL1424623 | 0.96 | CA5A (0.50) | CA5ACA5BTSHRCA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110339394-A | A kind of material preparing bone defect repair support and preparation method | 陶合体科技(苏州)有限责任公司 | 2019-10-18 | — | — | CN | claimed |
| CN-116675450-A | Low-temperature sintered low-heat silicate cement and preparation method thereof | 中国建筑材料科学研究总院有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20200315923-A1 | DESINFECTANT BONE AND DENTAL FILLER MATERIALS COMPRISING LIPOSOMES | CEMENTIC (FR) | 2020-10-08 | — | — | US | disclosed |
| EP-3691603-A1 | DESINFECTANT BONE AND DENTAL FILLER MATERIALS COMPRISING LIPOSOMES | Cementic (FR) | 2020-08-12 | — | — | EP | disclosed |
| EP-1648347-A1 | DEVICES FOR TREATING DEFECTS IN THE TISSUE OF A LIVING BEING | KENSEY NASH CORPORATION (US) | 2006-04-26 | — | — | EP | disclosed |
| EP-1646411-A1 | COMPLIANT OSTEOSYNTHESIS FIXATION PLATE | KENSEY NASH CORPORATION (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005009499-A1 | COMPLIANT OSTEOSYNTHESIS FIXATION PLATE | KENSEY NASH CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005004755-A1 | DEVICES FOR TREATING DEFECTS IN THE TISSUE OF A LIVING BEING | KENSEY NASH CORPORATION (US) | 2005-01-20 | — | — | WO | disclosed |