Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.68 |
| ▸ | HTR1D | P28221 | 9/20 | 0.68 |
| ▸ | HTR1B | P28222 | 9/20 | 0.68 |
| ▸ | HTR1A | P08908 | 8/20 | 0.68 |
| ▸ | HTR2C | P28335 | 6/20 | 0.68 |
| ▸ | HTR7 | P34969 | 5/20 | 0.68 |
| ▸ | DRD2 | P14416 | 3/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.68 |
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194700 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL29386932 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL3619305 | 0.80 | HTR6 (0.53) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6977773 | 0.80 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL3946582 | 0.79 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR2C | |
| SCHEMBL3620585 | 0.76 | HTR6 (0.49) | HTR6HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL3614689 | 0.75 | HTR6 (0.53) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL3626769 | 0.75 | HTR6 (0.48) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL3622734 | 0.74 | HTR6 (0.55) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL6980956 | 0.74 | HTR6 (0.77) | HTR6HTR1DHTR1BHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144883-B2 | Bicyclic sulfonamide compounds | BIOVITRUM AB (SE) | 2006-12-05 | — | — | US | disclosed |