Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 1.00 |
| ▸ | HTR1D | P28221 | 8/20 | 1.00 |
| ▸ | HTR1B | P28222 | 8/20 | 1.00 |
| ▸ | HTR1A | P08908 | 7/20 | 1.00 |
| ▸ | HTR7 | P34969 | 4/20 | 0.83 |
| ▸ | HTR2A | P28223 | 2/20 | 0.83 |
| ▸ | HTR2C | P28335 | 5/20 | 0.81 |
| ▸ | HTR2B | P41595 | 2/20 | 0.79 |
| ▸ | DRD2 | P14416 | 2/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 2/20 | 0.69 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194700 | 0.82 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL29386932 | 0.82 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6977773 | 0.81 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL3949519 | 0.79 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL6047115 | 0.79 | HTR6 (0.68) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL3948620 | 0.77 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL2924886 | 0.76 | NCF1 (0.79) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL7465991 | 0.75 | HTR6 (0.88) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL6972216 | 0.75 | HTR6 (0.80) | HTR6HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL6981823 | 0.75 | HTR6 (0.80) | HTR6HTR1DHTR1BHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450806-B1 | USE OF SULFONAMIDE DERIVATIVES IN THE TREATMENT OF OBESITY OR FOR THE REDUCTION OF FOOD INTAKE | BIOVITRUM AB PUBL (SE) | 2009-04-29 | — | — | EP | claimed |
| US-20080171779-A1 | USE OF 5-HT6 ANTAGONISTS TO PREVENT RELAPSE INTO ADDICTION | SOLVAY PHARMACEUTICALS B.V. | 2008-07-17 | — | — | US | disclosed |
| US-20080171779-A1 | USE OF 5-HT6 ANTAGONISTS TO PREVENT RELAPSE INTO ADDICTION | SOLVAY PHARMACEUTICALS B.V. | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171779-A1 | USE OF 5-HT6 ANTAGONISTS TO PREVENT RELAPSE INTO ADDICTION | HTR6, HTR3B, HTR5A | HTR6 1/4885HTR1D 12/4885HTR1B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.