Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040717 | 0.74 | CYP2C9 (0.52) | CDK4CCND1LDHACYP3A4CYP2C9 | |
| SCHEMBL5045178 | 0.74 | CYP2C9 (0.52) | CDK4CCND1LDHACYP3A4CYP2C9 | |
| SCHEMBL6047154 | 0.70 | CDK4 (0.41) | CDK4CCND1LDHACYP3A4CYP2C9 | |
| Aza-Flavanone SCHEMBL1501991 | 0.64 | MAPT (0.56) | BRD4ALDH1A1LMNAMAPTCYP19A1 | |
| SCHEMBL6023774 | 0.63 | CYP3A4 (0.43) | CYP3A4CYP2C9NOS1 | |
| SCHEMBL3726983 | 0.61 | AR (0.43) | CDK4CCND1LDHABRD4ALDH1A1 | |
| SCHEMBL157619 | 0.61 | BRD4 (0.50) | LDHABRD4ALDH1A1LMNAMAPT | |
| SCHEMBL6247618 | 0.61 | BRD4 (0.50) | LDHABRD4ALDH1A1LMNAMAPT | |
| SCHEMBL9295153 | 0.61 | BRD4 (0.50) | LDHABRD4ALDH1A1LMNAMAPT | |
| SCHEMBL6172172 | 0.60 | BRD4 (0.44) | LDHABRD4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105676-B2 | Tetrahydropyridoethers | ALTANA PHARMA AG (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20040162310-A1 | Tetrahydropyridoethers | ALTANA PHARMA AG. | 2004-08-19 | — | — | US | disclosed |
| US-6436953-B1 | ANTISECRETORY AGENTS, GASTROINTESTINAL INFLAMMATORY DISEASES; (7R,8R,9R)-2,3-DIMETHYL-8-HYDROXY-7-METHOXY-9-PHENYL-7,8,9,10-TETRAHYDRO -IMIDAZO(1,2-H)-(1,7)NAPHTHYRIDINE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162310-A1 | Tetrahydropyridoethers | CYP7A1, CYP2E1, TPMT | CDK4 599/4885CCND1 1757/4885LDHA 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.