Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045178 | 0.79 | CYP2C9 (0.52) | CDK4CCND1CYP2C9CYP3A4PDE5A | |
| SCHEMBL5040717 | 0.79 | CYP2C9 (0.52) | CDK4CCND1CYP2C9CYP3A4PDE5A | |
| SCHEMBL6435217 | 0.75 | CYP3A4 (0.38) | CYP2C9CYP3A4PDE5APDE1APDE1B | |
| SCHEMBL5988436 | 0.72 | CYP3A4 (0.36) | CYP2C9CYP3A4ALDH1A1TSHRCASP1 | |
| SCHEMBL5988563 | 0.70 | CYP3A4 (0.35) | CYP2C9CYP3A4HPGDALDH1A1MEN1 | |
| SCHEMBL6047152 | 0.70 | CDK4 (0.39) | CDK4CCND1CYP2C9CYP3A4LDHA | |
| SCHEMBL5989153 | 0.69 | CYP3A4 (0.34) | CYP2C9CYP3A4ALDH1A1TSHR | |
| SCHEMBL5840196 | 0.66 | CYP3A4 (0.41) | CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL5634281 | 0.65 | CYP3A4 (0.41) | CYP2C9CYP3A4BRD4ALDH1A1CYP1A2 | |
| SCHEMBL3726983 | 0.65 | AR (0.43) | CDK4CCND1LDHABRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105676-B2 | Tetrahydropyridoethers | ALTANA PHARMA AG (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20040162310-A1 | Tetrahydropyridoethers | ALTANA PHARMA AG. | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162310-A1 | Tetrahydropyridoethers | CYP7A1, CYP2E1, TPMT | CDK4 599/4885CCND1 1757/4885CYP2C9 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.