Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047264 | 1.00 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6047205 | 0.83 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6047207 | 0.83 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6047223 | 0.77 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6047201 | 0.73 | ADORA2A (0.50) | ADORA2AADORA1ADORA2B | |
| SCHEMBL12612295 | 0.71 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B | |
| SCHEMBL5653322 | 0.71 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6047272 | 0.70 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6628284 | 0.70 | ADORA2A (0.65) | ADORA2AADORA1 | |
| SCHEMBL6047254 | 0.70 | ADORA2A (0.54) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1544200-A1 | 1,2,4 -TRIAZOLO 1,5-c PYRIMIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ADORA1 2/4885ADORA2B 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.