Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839852 | 1.00 | EPHX1 (1.00) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL22754575 | 1.00 | EPHX1 (1.00) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL657100 | 1.00 | EPHX1 (1.00) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL3839853 | 1.00 | EPHX1 (1.00) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL12648363 | 0.89 | EPHX1 (0.87) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL655373 | 0.89 | EPHX1 (1.00) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL11492082 | 0.89 | EPHX1 (0.79) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL14403051 | 0.87 | EPHX1 (0.77) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL7775683 | 0.87 | EPHX1 (0.77) | EPHX1MEN1TP53CYP1A2CYP2C9 | |
| SCHEMBL7112702 | 0.87 | EPHX1 (0.77) | EPHX1MEN1TP53CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127616-B1 | Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it | TOSOH CORP (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1366815-B1 | Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it | TOSOH CORP (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6878835-B2 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1439001-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-20040116721-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6680275-B2 | COMPLEX OF OPTICALLY ACTIVE BINAPHTHOL, LANTHANUM TRIISOPROPOXIDE OXIDE, TRIPHENYLPHOSPHINE OXIDE AND CUMENE OR TERT-BUTYL HYDROPEROXIDE; OPTICAL PURITY; REACTIVITY; STABILITY | TOSOH CORPORATION (JP) | 2004-01-20 | — | — | US | disclosed |
| EP-1366815-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-20010051737-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-1127616-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6201123-B1 | FOR ASYMMETRIC EPOXIDATION OF ENONES; GIVES EPOXIDES HAVING AN ENHANCED OPTICAL PURITY | TECHNO POLYMER CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051737-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | SQLE, ENO1, GPX4 | EPHX1 19/4885MEN1 3111/4885TP53 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.