Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047640 | 0.79 | MAPT (0.36) | KMT2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5887166 | 0.74 | CYP2A6 (0.34) | KMT2AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL12019937 | 0.74 | IDO1 (0.59) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL12019868 | 0.74 | IDO1 (0.59) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL12019777 | 0.74 | IDO1 (0.64) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL7753164 | 0.74 | IDO1 (0.64) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL12019841 | 0.74 | IDO1 (0.64) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL6047637 | 0.72 | IDO1 (0.37) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL6047663 | 0.69 | MAPT (0.35) | KMT2AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5887835 | 0.69 | IDO1 (0.42) | IDO1EP300KAT8IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |