Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047640 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6047604 | 0.81 | IDO1 (0.35) | MAPTKDM4EALDH1A1LMNANQO1 | |
| SCHEMBL6047596 | 0.79 | ABL1 (0.45) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6047633 | 0.74 | PTPN1 (0.36) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL4009020 | 0.73 | GSTP1 (0.35) | SMN1; SMN2KDM4EALDH1A1ALOX5MEN1 | |
| SCHEMBL6047648 | 0.73 | NAAA (0.42) | GPR84BRD4 | |
| SCHEMBL6047638 | 0.71 | MAPT (0.34) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8197756 | 0.69 | NQO1 (0.54) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6047613 | 0.69 | THRA (0.39) | MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6047602 | 0.69 | NAAA (0.37) | MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |