SCHEMBL6047833

SCHEMBL6047833

C[Si](Br)(Br)c1ccccc1.C[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
MAPT P10636 1/20 0.33
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144807 0.87 ESR1 (0.44) ESR1ESR2MAPTNR1H2NR1H3
SCHEMBL190639 0.87 ESR1 (0.44) ESR1ESR2MAPTNR1H2NR1H3
SCHEMBL6519029 0.80 ESR1 (0.39) ESR1ESR2MAPTNR1H2NR1H3
SCHEMBL9359904 0.80 ESR1 (0.39) ESR1ESR2MAPTNR1H2NR1H3
SCHEMBL18108302 0.77 ESR1 (0.41) ESR1ESR2MAPTNR1H2NR1H3
SCHEMBL8378715 0.73 CYP1A2 (0.46) ESR1ESR2MAPT
SCHEMBL28979153 0.73 ESR1 (0.34) ESR1ESR2
SCHEMBL11128894 0.73 ESR1 (0.34) ESR1ESR2MAPT
SCHEMBL11296187 0.73 ESR1 (0.34) ESR1ESR2
SCHEMBL706216 0.73 ESR1 (0.32) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1712530-A2 Method of photocatalytically making the surface of base material ultrahydrophilic, base material having ultrahydrophilic and photocatalytic surface, and process for producing said material TOTO LTD. (JP) 2006-10-18 EP disclosed
EP-0816466-A1 METHOD OF PHOTOCATALYTICALLY MAKING THE SURFACE OF BASE MATERIAL ULTRAHYDROPHILIC, BASE MATERIAL HAVING ULTRAHYDROPHILIC AND PHOTOCATALYTIC SURFACE, AND PROCESS FOR PRODUCING SAID MATERIAL TOTO LTD. (JP) 1998-01-07 EP disclosed