Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14717198 | 0.87 | MAOB (0.46) | NPC1RAB9AKMT2AFGF23MAOB | |
| SCHEMBL28306530 | 0.87 | RAB9A (0.39) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL9647725 | 0.82 | KDM1A (0.34) | PIN1 | |
| SCHEMBL9647720 | 0.82 | KDM1A (0.34) | PIN1 | |
| SCHEMBL646883 | 0.82 | HPGD (0.37) | NPC1RAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL4203199 | 0.81 | NPC1 (0.39) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL4203197 | 0.81 | NPC1 (0.39) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL2010366 | 0.80 | KDM1A (0.33) | PIN1 | |
| SCHEMBL4207047 | 0.79 | RELA (0.53) | NPC1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL8677164 | 0.78 | MAOB (0.39) | NPC1RAB9ALMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |